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Abdominal Aortic Aneurysms


An AAA is an increase in aortic diameter by greater than 50% of normal
Usually regarded as aortic diameter of greater than 3 cm diameter
More prevalent in elderly men
Male : female ratio is 4:1
Risk factors - hypertension, peripheral vascular disease, family history
Accounts for 2% male deaths above the age of 55 years
3000 elective and 1,500 emergency operations in Maharashtra each year
Mortality of emergency operation is greater than 50%
Mortality of elective surgery is less than 5%
Selection of patients for operation depends on risk of operation vs. risk of rupture

Natural history

AAA diameter expands exponentially at approximately 10% / year
Risk of rupture increases as aneurysm expands
5 year risk of rupture:
 
5.0 - 5.9 cm = 25%
6.0 - 6.9 cm = 35%
More than 7 cm = 75%
Overall only 15% aneurysms ever rupture
85% of patients with a AAA die from an unrelated cause

Screening

AAA are suitable for screening as elective operation of asymptomatic aneurysms can reduce mortality associated with rupture
Who should be screened?
Probably males over 65 years - especially hypertensives
Single US at 65 years reduces death from ruptured AAA by 70% in screened population
Patients with small aneurysms should undergo regular surveillance
Repeated ultrasound every 6 months

Clinical features

75% are asymptomatic
Possible symptoms include:
 
Epigastric pain
Back pain
Malaise and weight loss (with inflammatory aneurysms)
Rupture presents with:
 
Sudden onset abdominal pain
Hypovolaemic shock
Pulsatile epigastric mass
Rare presentations include:
 
Distal embolic features
Aorto-caval fistula
Primary aorto-intestinal fistula

Indication for operation

Rupture
Symptomatic aneurysm
Rapid expansion
Asymptomatic > 6 cm - exact lower limit controversial

Pre-operative investigation

Pre-operative Investigation
Need to determine
 
Extent of aneurysm
Fitness for operation
Ultrasound, conventional CT and more recently spiral CT
Determines - aneurysm size, relation to renal arteries, involvement of iliac vessels
Most significant post op morbidity and mortality related to cardiac disease
If pre-operative symptoms of cardiac disease need cardiological opinion
May need thallium scan or cardiac catheterisation
Cardiac revascularisation required in up to 10% patients

Endovascular aneurysm repair

Introduced into clinical practice with few clinical trials over the past 10 years
Exact role unclear and medium and late-complications only recently recognised
Morbidity of conventional open aneurysm surgery related to:
 
Exposure of infra-renal aorta
Cross clamping of aorta
Endovascular repair may be associated with:
 
Reduced physiological stress
Reduced morbidity
Reduced mortality

Technique

Endovascular repair achieved by transfemoral or transiliac placement of prosthetic graft
Proximal and distal cuffs / stents anchor graft
Exclude aneurysm from circulation
Three main types of graft
 
Aorto-aortic
Bifurcated aorto-iliac
 
Aorto-uniiliac graft with femoro-femoral crossover and contralateral iliac occlusion

Types of Graft

Abdominal Aortic Aneurysms
Use of technique depends on aneurysm morphology
Aneurysm morphology is best assessed with spiral CT
Only ~40% of aneurysms suitable for this type of repair
Aorto-aortic grafts less frequently used due to high complication rate
Successful stenting associated with reduced aneurysm expansion
Still has 1% per year risk of aneurysm rupture

Complications

Graft migration
Endovascular leak
Graft kinking
Graft occlusion

Popliteal artery aneurysms

Defined as a popliteal artery diameter greater than 2 cm
Account for 80% of all peripheral aneurysms
50% are bilateral
50% are associated with an abdominal aortic aneurysm
50% are asymptomatic
Symptomatic aneurysms present with features of:
 
Compression of adjacent structures (veins or nerves)
Rupture
 
Limb ischaemia due to emboli or acute thrombosis
Treatment is by proximal and distal ligation
Revascularisation of the leg with a femoropopliteal bypass
With a symptomatic popliteal aneurysm 20% patients will undergo an amputation

Dr. Pankaj Patel a vascular surgeon has expertise in peripheral vascular diseases, varicose veins and deep vein thrombosis